title en

Journal archive > 2013 > N 1 January-February

THE GLUTATHIONE SYSTEM IN THE BLOOD OF RATS
AND MORPHOLOGICAL CHANGES OF THE PANCREAS UNDER EXPERIMENTAL
ACUTE AND CHRONIC PANCREATITIS

V. A. Makarchuk1, G. O. Ushakova2, O. O. Krylova1

1SI Institute of Gastroenterology, National Academy of Medical Sciences of Ukraine, Dnipropetrovsk;
2Oles’ Gonchar Dnipropetrovsk National University, Ukraine;
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In experiment on laboratory rats the models of acute and chronic pancreatitis were developed to study the changes of lipoperoxidation-antioxidant protection system depending on morphological changes of the pancreas. The acute and chronic pancreatitis is accompanied with intensification of lipoperoxidation and gradual inhibition of antioxidant system due to development of subsequent chronization of the pathological process.

Key words: malonic dialdehyde, exchange enzymes of glutathione, acute pancreatitis, chronic pancreatitis.

The original article in Ukrainian is available for download in PDF format.

© The Ukrainian Biochemical Journal