ESTIMATION OF THE ROS IN THE PRESENCE OF BIOLOGICALLY ACTIVE SUBSTANCES BY POROUS SILICON FLUORESCENCE (V.B. Shevchenko, O.I. Dacenko, O.V. Shablykin, T.V. Osadchuk, A.M. Lyakhov, Y.V. Pivovarenko, V.A. Makara)

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Journal archive > 2012 > N 4 July-August

ESTIMATION OF THE ROS IN THE PRESENCE OF BIOLOGICALLY ACTIVE

SUBSTANCES BY POROUS SILICON FLUORESCENCE

V. B. Shevchenko¹, O. I. Dacenko¹, O. V. Shablykin², T. V. Osadchuk², A. M. Lyakhov², Y. V. Pivovarenko³, V. A. Makara^1,3

¹Taras Shevchenko Kyiv National University, Ukraine;

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²Institute of Bioorganic Chemistry and Petroleum Chemistry, National Academy of Sciences of Ukraine;

³STC Physico-Chemical Center of Materials Science of Taras Shevchenko Kyiv National University and NAS of Ukraine

The fluorescence spectra of the porous silicon modified by water solutions of biologically active materials and materials of biological origin are recorded as well as the fluorescence spectra of the porous silicon modified by lecithin monolayers grown on the surface of water solutions of the biologically active materials. The analysis of the obtained spectra made it possible to conclude on the effect of the studied materials on the content of ROS.

Key words: porous silicon, photoluminescence, DNA, RNA, furin, diphenylhydramine hydrochloride, isadrin.

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