Journal archive > 2011 > N 6 November-December

BIOCHEMICAL FEATURES OF CANCER CACHEXIA UNDER CONDITIONS OF DIFFERENT PROVISION WITH VITAMIN A

I. O. Shmarakov, N. V. Gnep, M. M. Marchenko

Yuriy Fedkovych Chernivtsi National University, Ukraine;
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On the model of tumor growth of Guerin’s carcinoma and experimental modeling of vitamin A provision the biochemical characteristics of tumor cachexia in animals with malignant tumors and different vitamin A provision status were studied. It is determined that tumor growth in the body, deprived of vitamin A, is characterized by negative nitrogen balance, decrease of glucose, free fatty acids and ketone bodies level in the blood serum, which indicates the increase of cancer cachexia.

Key words: vitamin A, tumor growth, Guerin’s carcinoma.

The original article in Ukrainian is available for download in PDF format.

© The Ukrainian Biochemical Journal