Journal archive > 2011 > N 1 January-February

AN ESTIMATE OF PROTEIN SYNTHESIS IN LIVER UNDER INDUCED HEPATITIS

V. A. Hryschenko1, V. A. Tomchuk1, O. M. Lytvynenko1, V. O. Chernyshenko2,3, V. I. Gryschuk2, T. M. Platonova2

1National University of Life and Environmental Sciences of Ukraine, Kyiv;
2Palladin Institute of Biochemistry, National Academy of Science of Ukraine, Kyiv;
3Taras Shevchenko Kyiv National University, Ukraine;
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Liver protein synthesis was estimated comparing the levels of prothrombin and its inactive form PIVKA-prothrombin. The latter indicates liver dysfunction. These diagnostic tests allow monitoring the effectiveness of the commonly applied preparation “Essentiale Forte” and that of the liposomal form of the biologically active additive (BAA) FLP-MD based on phospholipids of various origin.

Key words: toxic hepatitis, PIVKA-prothrombin, diagnostic.

The original article in Ukrainian is available for download in PDF format.

 

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