Journal archive·· 2010· ·#4 July-August

INFLUENCE OF RIBOXINE ON PROCESSES OF LIPID PEROXIDATION
AND ACTIVITY OF ANTIOXIDANT ENZYMES IN RATS’ THYMOCYTES
UNDER RADIATION INJURY

V. V. Polyakova, N. G. Raksha, L. P. Dragan, T. R. Andriichuk

Taras Shevchenko Kyiv National University, Ukraine;
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The disorders of oxidative homeostasis with accumulation of lipid peroxidation products upon depletion of functional capacity of antioxidant defense in thymus lymphocytes after irradiation in doses of 1.0 and 7.78 Gy were shown. The riboxine injection leads to normalization of balance in prooxidant-antioxidant system (with a decrease of formation of lipid peroxidation and activation of antioxidant enzyme system) in early terms after X-ray exposure.

Key words: thymus lymphocytes, X-ray irradiation, prooxidant-antioxidant system, riboxine.

The original article in Ukrainian is available for download in PDF format.