Journal archive > 2010 > N 6 November-December

CHARACTERISTIC OF?CARBOHYDRATE COMPONENTS OF CHICKENS AND HUMAN’S FIBRONECTINS

M. V. Kovalenko1, L. M. Stepchenko1, А.?O.?Kulinich2, A. I. Shevtsova2

1Dnipropetrovsk State Agrarian University, Ukraine;
2Dnipropetrovsk State Medical Academy, Ukraine;
e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

The paper presents new information about the carbohydrate structures of 39-days chicken’s fibronectin. It is found out that chicken fibronectin contains mainly biantennary N-glycans with a core fucose and fucosylated O-glycans. It is shown that N-glycans of chicken fibronectin are poorly sialated, since this protein exhibits affinity for the PNA and weak binding to sialospecific SNA. A comparative analysis of lectin-binding activity of chicken and human fibronectins has shown that both glycoproteins differ in glycan composition.

Key words: fibronectin, carbohydrate structure, affinity chromatography, N-glycans, lectin, chickens.

?The original article in Ukrainian is available for download in PDF format.