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Journal archive > 2009 > N 3 May-June

GLYCOSAMINOGLYCANES OF CARTILAGE TISSUE AFTER
THE MECHANICAL TRAUMA: THE?INFLUENCE OF LOW-MOLECULAR FRACTION
FROM THE?CORD BLOOD AND BLOOD OF?VEAL CALVES

A. K. Gulevsky, V. I. Grishchenko, E. G.?Ivanov

Institute for Problems of Cryobiology and Criomedicine, National Academy of Sciences of Ukraine, Kharkov;
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Influence of low-molecular fraction (to 5?kDa) from cord blood (FCB) compared with «Actovegin» derived from the blood of veal calves on the content of the matrix polysaccharide components from and proteins of the cartilage connecting tissue after the mechanical trauma was investigated. It is established, that intramuscular administration of FCB essentially stimulates the accumulation of the basic components of the mat­rix: hexosamine, uronic acid, hyaluronic acid, chondroitinsulfate and heparin, and also the most important components of structural proteins in the cartilage regenerate of the rat knee joint.

Key words: cartilage, mechanical trauma, cord blood of cow, preparation «Actovegin», rats, glycosaminoglycanes, proteoglycanes, amino?acids.

The original article in Russian is available for download in PDF format.

© The Ukrainian Biochemical Journal