Journal archive > 2009 > N 2 March-April

THE INFLUENCE OF STRESS ON THE CONTENT OF FREE RADICAL OXIDATION
PRODUCTS IN SUBCELLULAR BRAIN FRACTIONS IN RATS AT PUBERTAL AGE

Y. V. Volkova, V. V. Davydov

SI «Institute of Children and Adolescent Health Care, Academy of Medical Sciences of Ukraine», Kharkоv;

The purpose of the present work is to study the influence of immobilization stress of different intensity on the content of protein and lipid oxidation products in subcellular brain fractions in rats of different age. It has been shown that 30-minute immobilization of 1.5-month-, 2-month- and 12 month-old rats was not accompanied by accumulation of protein and lipid oxidation products in subcellular brain fractions. A prolonged immobilization of 1.5-month-old rats was accompanied by manifestations of oxidative stress in subcellular brain fractions; such manifestations were not charac­teristic of the rats of older age groups.

Key words: immobilization, oxidative stress, adaptation, brain, puberty, mitochondria, microsomes.

The original article in Russian is available for download in PDF format.

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