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Journal archive > 2008 > N 4 July-August

METABOLISM INTENSITY AND UBIQUINONE AND UBICHROMENOL CONTENT
IN RATS’ LIVER UNDER А,Е-HYPOVITAMINOSIS

G. V. Donchenko, O. B. Kuchmenko, D. M. Petukhov, O. M. Palivoda, L.O. Chernukhina

Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, Kyiv;

The paper is dedicated to the study of peculiarities of ubiquinone and ubichromenol distribution and metabolism in subcellular fractions of rats’ liver under A,E-hypovitaminosis. It is shown, that dietary deprivation of vitamins A and E leads to a sharp decrease in intensity of CoQ biosynthesis in rats’ liver tissue and to its intracellular redistribution. Under these circumstances the observed decrease in the inclusion of labelled tyrosine in rats’ liver CoQ under A,E-hypovitaminosis may be really caused by dietary deprivation of vitamin E.

Key words: ubiquinone, ubichromenol, A,E-hypovitaminosis.

The original article in Ukrainian is available for download in PDF format.

© The Ukrainian Biochemical Journal