G. V. Donchenko, O. B. Kuchmenko, D. M. Petukhov, O. M. Palivoda, L.O. Chernukhina
The paper is dedicated to the study of peculiarities of ubiquinone and ubichromenol distribution and metabolism in subcellular fractions of rats’ liver under A,E-hypovitaminosis. It is shown, that dietary deprivation of vitamins A and E leads to a sharp decrease in intensity of CoQ biosynthesis in rats’ liver tissue and to its intracellular redistribution. Under these circumstances the observed decrease in the inclusion of labelled tyrosine in rats’ liver CoQ under A,E-hypovitaminosis may be really caused by dietary deprivation of vitamin E.
Key words: ubiquinone, ubichromenol, A,E-hypovitaminosis.
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