PECULIARITIES OF LEUCOTRIENES METABOLISM IN THE RAT ORGANISM UNDER E-HYPOVITAMINOSIS
S. B. Silonov, G. V. Donchenko, R. P. Morozova
Some changes take place in the spectrum of fatty acid, cholesterol and individual phospholipids’ composition in the rat liver, under E-hypovitaminosis, that can play a considerable role in the cell damage. The level of cysteinyl leucotriene decreases in the blood and liver under E-hypovitaminosis and it rises to the control level under vitamin?Е correction. This demonstrates the influence of tocopherol on 5-LO pathway arachidonic acid.
Key words: arachidonic acid, tocopherol, E-deficiency diet, phospholipids, leucotrien.
The original article in Ukrainian is available for download in PDF format.
© The Ukrainian Biochemical Journal