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Journal archive > 2007 > N 6 November-December

PROCESS OF PLATELETS ACTIVATION BY STREPTOKINASE

N. K. Burlova-Vasyl’eva, I. M. Krasnobryzha, A. M. Savchuk, G. L. Volkov

Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, Kyiv;

This study concerns the influence of streptokinase and antistreptokinase antibodies on rabbits platelets in blood plasma depleted of plasminogen. The immune complex streptokinase-antibody causes platelets activation, whereas other investigated immune complexes didnot express such activity. Platelets aggregation wasnot detected in any case. It was determined that streptokinase induces platelets activation in the rabbit plasma with high titre of antistreptokinase antibodies in absence of plasminogen.

Key words: streptokinase, antistreptokinase antibody, platelets.

The original article in Ukrainian is available for download in PDF format.

© The Ukrainian Biochemical Journal