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Journal archive > 2007 > N 4 July-August


L. D. Varbanets1, O. N. Rzaeva1, I.?I.?Seifullina2, E. E. Martsinko2, A. G. Pesaroglo2,
T. O. Philippova2, Z. I. Zhilina2, Yu. V. Ishkov2, E. V. Karpenko3, A. N. Shulga3
1Zabolotny Institute of Microbiology and Virology, National Academy of Sciences of Ukraine, Kyiv;
e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.;
2Mechnikov Odessa National University, Ukraine;
3Lviv Department of Institute of Physical Chemistry, National Academy of Sciences of Ukraine

For the first time the influence of a number of synthetic porfirin and fluoren derivatives, coordinative germanium substances and surfactants on the biosynthesis and activity of Penicillium commune 266 ?-L-rhamnosidase has been studied. It is shown that some of porfirin derivatives and coordinative germanium substances may be used as inducers of biosynthesis (143–430%) and also as stimulators of ?-L-rhamnosidase activity (15–44%). It is more expedient to use biscitratgermanium acid in a complex with asparaginic acid (430%) or threonine (370%) as inducers of biosynthesis of enzyme. At the same time the use of porfirin derivatives, in particular meso-tetra(N-methyl-6-chinoline)porfirin tosilate or its manganese complex, is more efficient as stimulators (40%) of ? L-rhamnosidase activity. The utilization of such surfactants as tregaloso-, peptido- and rhamnolipids is not expedient. These compounds either do not influence or inhibit biosynthesis and activity of P. commune ?-L-rhamnosidase. Only in concentration of 0.01% rhamnolipid increased the activity of enzyme by 7.5%.

Key words: ?-L-rhamnosidase, Penicillium commune, porfirin and fluoren derivatives, coordinative germanium compounds, surfactants.

The original article in Ukrainian is available for download in PDF format.

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