PECULIARITIES IN LIPID COMPOSITION OF BLOOD SERUM LIPOPROTEINS UNDER INSULIN RESISTANCE (V.V. Sokolik, V.S. Chursina, O.S. Rodenko, G.Kh. Bozhko)

title en

Journal archive > 2007 > N 2 March-April

PECULIARITIES IN LIPID COMPOSITION OF BLOOD SERUM LIPOPROTEINS

UNDER INSULIN RESISTANCE

V. V. Sokolik, V. S. Chursina, O. S. Rodenko, G. Kh. Bozhko

Institute of Neurology, Psychiatry and Narcology, Academy of Medical Sciences of Ukraine, Kharkiv;

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The purpose of this investigation was to study lipid composition of apoB- and apoA-containing lipoproteines in conditions of insulin resistance pathology. It was shown that hypertriglycerolemia and hypercholesterolemia were determined by triglycerole and cholesterol surplus in the composition of both apoB- and apoA-containing lipoproteins. Phospholipid deficiency in the composition of all lipoproteins fractions were established. Possible mechanisms of formation and metabolism in circulation of blood lipoproteins with altered lipid composition in the blood flow at insulin resistance is discussed.

Key words: lipoproteins, triglyceroles, cholesterol, phospholipids, insulin resistance.

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