Journal archive > 2005 > N2, March-April

Composite template membranes as synthetic receptor systems. 1. Preparation, specificity and template effect

V. M. Kochkodan, V. V. Goncharuk 

Molecularly impregnated membranes for selective recognizing of adenosine 3?,5?-cyclic monophosphate (cAMP) were obtained and their separation properties were studied. Composite polyvinylidenfluoride microfiltration membranes covered with a thin layer of polymer impregnated with cAMP were prepared using photoinitiated copolymerization of dimethylaminoethylmethacrylate as a functional monomer and trimethylolpropane thrimethacrylate as a cross-linker in the presence of cAMP as a template. It was concluded that the ability of MIP membranes to selective binding of cAMP is a result of both specific shape and dimension of the recognizing site as well as specific interactions between functional groups responsible for selective template binding inside the receptor site.

Recieved: 2004-11-12

Published at the site: 2005-03-03

The original article in Ukrainian is available for download in PDF format.

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