Journal archive > 2004 > N 6, November-December

The role of the tissue type plasminogen activator and its inhibitor in haemostasis system function in norm and with pathology

E. M. Krasnobryzha, O. M. Savchuk, T. M. Platonova, G. L. Volkov

The paper is dedicated to the study of structure and physiological functions of tissue type plasminogen activator and its inhibitor PAI-1, changes of these parametres in normal and pathology conditions. The interrelation of the coagulation and the fibrinolytic system during the range of pathologies was studied. It was demonstrated that simultaneous analysis of the coagulation and fibrinolytic systems analysis allow to diagnose the thrombotic complications.

Recieved: 2004-02-06

Published at the site: 2005-12-15

The original article in Ukrainian is available for download in PDF format.