Journal archive > 2004 > N3, May-June

Catalase and glutathione-peroxidase: qualitatively different correlations with the rate of oxygen consumption

Kh. K. Muradian, N. A. Utko, T. G. Mozzhukhina, I. N. Pishel, V. Fraifeld, A. Ya. Litoshenko

Correlative relations of the liver supernatant enzymatic activity of catalase (CAT) and glutathione-peroxidase (GP) with the velocities of oxygen consumption (VO2) and carbon dioxide exhalation (VCO2) were analyzed by the two- and three-dimensional linear and non-linear statistical methods in mice. It is shown that despite the close functions, CAT and GP, nevertheless, exhibit opposite correlative and regressive links with the gaseous exchange indices. As was found by the pairwise linear method, the activity correlation with VO2 was positive for CAT, but negative for GP. The opposite patterns of correlation were also apparent under the three-dimensional non-linear analysis.

Recieved: 2003-12-20

Published at the site: 2004-06-06

The original article in Russian is available for download in PDF format.